Nayyab Ali is a transgender rights defender and Chairperson of the All Pakistan Transgender Election Network. She also manages the ‘Khawaja Sira Community Centre’ in Okara, which offers a basic literacy and numeracy programme, vocational training, life skills education and driving classes for the transgender community. In 2018, Nayyab was one of the four transgender candidates who ran for Pakistan's general elections. Nayyab has also been leading the advocacy efforts for the approval of the Pakistan’s National Transgender Rights Protection Policy.
Pakistan became one of the first countries to legally recognise a third sex on its national ID cards almost a decade ago and extended this to its passports in 2017. However, discrimination and violence persist. Nayyab herself has also faced numerous threats and physical attacks, and she survived an acid attack.