Front Line is profoundly concerned by reports received concerning the continued detention and deteriorating health condition of human rights defender, Mr Alisher Karamatov, who has been detained since June 2006 and has been denied necessary medical treatment. Alisher Karamatov is the Chairperson of the Human Rights Society of Uzbekistan (HRSU), Mirzaabad region. He has served two years of a nine year sentence for “extortion” following a trial which international observers defined as “deeply flawed” and “unfair”.